Tag Archives | pharma market analysis

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2014 is the year of Immuno-Oncology

One of the hot topic of conversation amongst the VCs at the JP Morgan Healthcare conference in San Francisco this past week was the field of immuno-oncology. We have already seen significant excitement in anti-PD1/PD-L1 drugs and their early promise in melanoma, renal and lung cancers. Taking a more strategic view, however, the question is […]

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Macrophage Cell Surface Protein S100A10 may be new target

Sally Church, PhD on Pharma Strategy Blog has written about research on macrophage cell surface protein S100A10 and the role this plays in cancer metastasis and tumor growth. As Sally notes, “macrophages are critical in driving tumour growth, invasion and metastasis.  Macrophages are like the Pacmen of cells…”  What a great visual metaphor! Recently published […]

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Analyzing the cost of Seattle Genetics Adcetris (brentuximab vedotin)

Earlier this summer, the Food and Drug Administration (FDA) Oncology Drugs Advisory Committee (ODAC) announced a positive decision for Seattle Genetics’ Adcetris™ (brentuximab vedotin) in Hodgkin Lymphoma (HL) and Analplastic Large Cell Lymphoma (ALCL). As Sally Church on Pharma Strategy Blog reported earlier this week, Seattle Genetics has just received fast track approval from the […]

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What role does PTEN loss play in non-melanoma skin cancer?

At ASCO this year, there was a lot of interest in BRAF mutated melanoma, with data being presented in the plenary session on vemurafenib (PLX4032) and ipilimumab. However, as Sally Church on Pharma Strategy Blog points out, 40% of all new cancer cases are due to non-melanoma skin cancer, with over one million diagnoses each […]

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Metastatic Melanoma Competitor and Market Analysis

One of the services that Icarus Consultants offers is to monitor competitor activity in a market, therapeutic area or pathway, and advise clients on new developments. For those interested in metastatic melanoma, this week saw Roche/Genentech make marketing applications to the FDA in the United States and European EMEA for PLX4032 (vemurafenib) in BRAF V600E […]

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Impact of healthcare reform on US pharma market

As marketing strategy consultants we are often called upon to look at the market opportunity in the United states for a company, a new drug or indication. In order to do this it’s necessary to keep on top of the regulatory and reimbursement challenges that pharmaceutical and biotechnology companies face in the U.S. market. Healthcare […]

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The increasing importance of mouse models in drug development

Mice seem to get bad PR; there’s far more people that like cats……..So in the interests of fair balance, we’d like to draw attention to the increasing importance of preclinical mouse models in cancer drug development. Pieter Droppert on Biotech Strategy Blog discusses how innovations in translational medicine, and improved mouse models of human cancer […]

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