Posts tagged ‘Gleevec’
EHA 2011 patient advocacy session missing two or three doses of CML therapy per month may have serious impact on outcome
June 16th, 2011
Have you ever failed to complete a course of antibiotics or missed the occasional dose of a cancer drug thinking it won’t kill you?
An interesting presentation by David Marin of the Hammersmith Hospital at the recent European Hematology Association (EHA) Congress in London highlighted how missing two or three doses per month of tyrosine kinase inhibitors for Chronic Myeloid Leukemia (CML) may have a dramatic effect on outcome.
Pieter Droppert on Biotech Strategy Blog has written more about the patient advocacy session at EHA 2011 where Dr Marin presented on CML adherence.
As Sally Church discusses on her EHA video blog, better patient and physician education is needed about adherence along with packaging of drugs that encourages compliance.
The take home is that even if you feel better, continuing to take a treatment may the right course of action in the long-term.
If you are interested in more information about CML adherence, then Jan Geissler, who chaired the EHA patient advocacy session, has posted more information on the CML Advocates Network website.
June 15th, 2011
In case you missed the 16th Congress of the European Hematology Association (EHA) that took place this past weekend in London, Sally Church has produced a video blog with her highlights from the meeting.
It’s tough doing ASCO and EHA back-to-back, but Sally is a seasoned road warrior. In the video we even see her working on the plane!
In her video blog, Sally talks about new data from the Congress in AML, systemic anaplastic large cell lymphoma (sALCL), and how pharma/biotech companies can do more with their drug packaging to help promote patient adherence to drug treatments.
Sally formerly worked at Novartis Oncology on imatinib (Gleevec®) in CML, so has expertise in this field. You can read more about EHA and hematology new products on Pharma Strategy Blog.
May 13th, 2011
One of our areas of focus at Icarus Consultants is helping pharma, biotech clients with their commercial strategy to bring new products to market. Sally Church worked in oncology new products at Novartis and brought Gleevec to market in the United States, so has first hand experience of what it takes to make this happen.
Key to new product success is understanding the market opportunity, and focusing your drug on targets that have both commercial and clinical justification. We spend a lot of our time writing powerpoint presentations that help clients make strategic new product development marketing and commercial decisions.
On Pharma Strategy Blog, Sally Church takes a look at the market for PARP inhibitors such as iniparib, olaparib and veliparib. She’s been writing about them since 2006!
Sally discusses the clinical trials that have taken place, and how poor trial design has contributed to the lack of success. You can read Sally’s in-depth review of what’s happening with the clinical development of PARP inhibitors on Pharma Strategy Blog.
May 5th, 2011
Sally Church invests a lot of her personal time in writing for Pharma Strategy Blog. With a focus on the science of new products and treatments in cancer and hematology, Sally willingly shares her passion, knowledge and expertise.
It is always a pleasure to receive endorsement from others. Matthew Herper from Forbes Health kindly highlighted Sally’s interview with Dr Charles Sawyers as a “must read.”
We agree. Dr Sawyers is one of the leading translational scientists in the United States who along with Dr Brian Druker and Dr Nick Lydon received the prestigious Lasker award for their work on imatinib (Gleevec/Glivec) in CML. Dr Sawyers is now working on prostate cancer, and in his interview with Sally, describes his latest work developing MDV3100 and ARN-509.
We unequivocally recommend reading Sally’s post on Pharma Strategy Blog, “Making a difference to the lives of cancer patients: An interview with Dr Charles Sawyers.”
April 12th, 2011
A venture capital firm in Boston yesterday bet $40M in first round financing that Dr Druker and his partners can repeat the success of Gleevec/Glivec with a new Boston/Cambridge life sciences start-up company, Blueprint Medicines.
If Daedalus had money to invest, a wager on Dr Druker would be as good as any in the biotechnology industry. After the successful development of Gleevec/Glivec, a tyrosine kinase inhibitor that Drs Druker & Lydon were instrumental in developing with Novartis for the treatment of chronic myeloid leukemia (CML), it’s hard not to believe that they cannot do it again.
Icarus Consultants’ Sally Church worked closely with Dr Druker while at Novartis Oncology. Starting in oncology new products she saw the potential of STI-571, and subsequently took the product to market in the U.S. market as Gleevec. We wish him well, and should Blueprint Medicines need any commercial, marketing strategy consulting services, we hope he’ll call us .
You can read more on Biotech Strategy Blog.
March 25th, 2011
Sally Church, PhD our oncology new products expert, is passionate about making a difference to the lives of patients with cancer. She channels her many talents and energies into helping pharma and biotech companies assess the best targets for their new products. It’s a job that requires science, marketing strategy and commercial awareness; a unique blend of skills.
Sally’s recent post on Pharma Strategy Blog entitled “Accelerated approval and cancer drugs” considers how best to bring new cancer drugs to market? Should promising oncology new products go from phase 2 clinical trials to market without the need for a large and expensive phase 3 registration study? If so, what happens when the data doesn’t pan out as happened with Roche/Genentech’s bevacizumab (Avastin) in breast cancer?
You can read more about Sally’s thoughts on Pharma Strategy Blog.
March 14th, 2011
Following on from news of Second Sight’s CE mark for its Argus™ II retinal prosthesis or “artificial retina”, Pieter Droppert looks at the collaboration between 6 U.S. National Laboratories and 4 Universities that developed the science behind this device.
In a post today on Biotech Strategy Blog, he looks at the power of collaboration by leading research institutions and asks whether such innovation could be led by a private company?
In our view, creating a high performing team that collaborates effectively is key to new product development success.
December 22nd, 2010
Published by Pieter Droppert on Biotech Strategy Blog
December 14th, 2010
Published by Sally Church on Pharma Strategy Blog